5 Simple Techniques For https://www.ceesdekker.net
5 Simple Techniques For https://www.ceesdekker.net
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Midway by means of his vocation, Cees Dekker reinvented himself. Right after decades of hardcore physics, he shifted his target to ‘nanobiology’ at the switch of the millennium. A phrase he coined himself, for a make a difference of actuality.
Our group studies bacterial cell division and is aiming to represent a ‘bottom up biology’ in artificial cells which can autonomously divide. Our key curiosity lies in cell division, chromatin framework, and spatial Management.
Across the exact time, the team of Paul McEuen, who was then based at the College of California, Berkeley, showed identical benefits on ropes of bundled nanotubes. With regards to the wrapping angle, nanotubes can come in metallic or semiconducting variants, a prediction that we and Charles Lieber’s team at Harvard University independently verified utilizing scanning tunnelling spectroscopy experiments.
Nanofabrication of electrodes with sub-5 nm spacing for transportation experiments on single molecules and metallic clusters
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Direct immobilization of indigenous yeast iso-1 cytochrome c on bare gold: rapid electron relay to redox enzymes and zeptomole protein-film voltammetry
What distinguishes biology from chemistry is these components jointly make up a living process. The secret of claimed existence, I do think, lies inside the interactions, the interaction of Individuals molecules. The massive issue about the origin of daily life is still unanswered. How did we ever evolve from uncomplicated molecules in to the particularly sophisticated devices we see these days? We don't know. I need to work on these kinds of massive, open up concerns.’
Researching DNA loop extrusion by SMC proteins for chromosome architecture with solitary-molecule assays.
The rotors harness Electrical power from the nanoscale drinking water and ion circulation that's created by a static chemical or electrochemical likely gradient inside the nanopore, that are founded by way of a salt gradient or applied voltage, respectively. These synthetic nanoengines self-organize and work autonomously in physiological problems, suggesting methods to developing Strength-transducing motors at nanoscale interfaces.
There was a single challenge nevertheless — we didn't notice any measurable electrical conduction from The one polymer molecules. We concluded that at the single-molecule level, conducting polymers were really not this sort of excellent conductors, which was relatively disappointing. We Consequently broadened our watch to test to search out additional promising molecules.
Given that 2000 he moved to single-molecule https://www.ceesdekker.net biophysics and nanobiology, with investigation from research of DNA loop extrusion and supercoiling to DNA translocation by way of nanopores. A lot more recently his investigation has focused on finding out chromatin structure and mobile division with bacteria on chip, when he can also be seeking to in the end Establish synthetic cells from The underside up.
Cees Dekker is Distinguished University Professor at TU Delft. Trained as a physicist, he pioneered nanotechnology with numerous discoveries on carbon nanotubes within the 1990s. Because 2000, he moved to single-molecule biophysics and nanobiology. His current research focuses on (i) nanopores for protein sequencing; (ii) chromosome composition, especially SMC motor protein; and (iii) creating a residing artificial cell from lifeless molecules. Dekker is definitely an elected member in the KNAW and fellow towards the APS and also the IOP.
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Dekker heeft fundamentele ontdekkingen gedaan op het gebied van koolstof nanobuisjes. Mede vanwege deze werkzaamheden is hij al jaren de meest geciteerde fysicus in Nederland. Tegenwoordig onderzoekt hij achieved enkel-molecuultechnieken de biofysica van moleculen in de biologische cel. Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond intelligent style and design in 2005. (nl)